Cyclins and CDKs

Hi, I’m not completely sure about Cyclins and CDKs, what they are and how they relate to the AP Bio exam. If you go over this I would appreciate that.

They are involved in the checkpoint system that happens in cell division. In the G2 phase checkpoint, MPF controls chromosome condensation, nuclear envelope breakdown, and spindle assembly. MPF is created by CDK and cyclin, CDK is always present but cyclin “cycles”, meaning it builds up to mitosis, peaks, and rapidly declines. On a graph, it appears as though cyclin is slowly progressing until mitosis and rapidly drops off, while MPF rapidly increases, peaks, and rapidly decreases at mitosis.

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